PUBLIKATIONSLISTA
Originalartiklar
Wennberg C, Lundborg M, Lindahl E, Norlén L (2023) Understanding Drug Skin Permeation Enhancers Using Molecular Dynamics Simulations. J. Chem. Inf. Model. 2023 Aug 14;63(15):4900-4911
Norlén L (2023) Molecular Organization of the Skin Barrier. Acta Derm Venereol. 2023 Nov 21:103:adv13356. doi:10.2340/actadv.v103.13356
Lundborg, M. Wennberg,C. Lidmar, J. Hess, B. Lindahl, E. Norlen, L (2022) Skin permeability prediction with MD simulation sampling spatial and alchemical reaction coordinates, Biophysical Journal, https://doi.org/10.1016/j.bpj.2022.09.009
Norlén, L. Lundborg, M. Wennberg, C. Narangifard, A. Daneholt, B (2022) The Skin’s Barrier: A Cryo-EM Based Overview of its Architecture and Stepwise Formation. J. Invest. Dermatol. 142:285-292
Narangifard, A. Wennberg, CL. den Hollander, L. Iwai, I. Han, H. Lundborg, M. et al. (2021) Molecular reorganization during formation of the human skin barrier studied in situ. J. Invest. Dermatol. 141(5):1243-1253.e6.
Norlén, L (2014) Update of technologies for examining stratum corneum. Br J. Dermatol. 171:13-18
Norlén, L (2013) Current understanding of skin barrier morphology. Skin Pharm. Phys. 26:213-216
Johnsen, GK. Norlén, L. Martinsen, Ö. Grimnes, S (2011) Sorption properties of the human stratum corneum. Skin Pharmacol. Physiol. 24:190-198
Norlén, L. Öktem, O, Skoglund, U (2009) Molecular cryo-electron tomography of vitreous tissue sections: current challenges. J. Microscopy 235:293-307
Plasencia, I. Norlén, L. Bagatolli, LA (2007). Direct visualization of lipid domains in human skin stratum corneum’s lipid membranes: effect of pH and temperature. Biophysical J. 93:3142-3155
Norlén, L. Plasencia, I. Simonsen, A. Descouts, P (2007) Human stratum corneum lipid organization as observed by atomic force microscopy on Langmuir-Blodgett films. J. Struct. Biol. 158:386-400
Norlén, L. Masich, S. Goldie, KN. Hoenger, A (2007) Structural analysis of vimentin and keratin intermediate filaments by cryo-electron tomography. Exp. Cell Res. 313:2217-2227
Masich, S. Östberg, T. Norlén, L. Shupliakov, O. and Daneholt, B (2006) A procedure to deposit fiducial markers on vitreous cryo-sections for cellular tomography. J. Struct. Biol. 156:461-468
Al-Amoudi, A. Dubochet, J. Norlén, L (2005) Nanostructure of the epidermal extracellular space as observed by cryo-electron microscopy of vitreous sections of human skin. J. Invest. Dermatol. 124:764-777
Norlén, L. Al-Amoudi, A (2004) Stratum corneum keratin structure, function, and formation: the cubic rod-packing and membrane templating model. J Invest Dermatol. 123(4):715-32
Al-Amoudi, A. Norlén, L. Dubochet, J (2004) Cryo-electron microscopy of vitreous sections of native biological cells and tissues. J Struct Biol. 148(1):131-5
Al-Amoudi, A. Chang, J-J. Leforestier, A. McDowall, A. Michel Salamin, L. Norlén, L. Richter, K. Sartori Blanc, N. Studer, D. Dubochet, J (2004) Cryo-electron microscopy of vitreous sections. EMBO J. 15;23(18):3583-8
Westerberg, R. Tvrdik, P. Undén, A-B. Månsson, J-E. Norlén, L. Jakobsson, A. Holleran, W. Elias, P.M., Asadi, A. Flodby, P. Toftgård, R. Capecchi, M. Jacobsson, A (2004) Role of ELOVL3 and fatty acid chain length in development of hair and skin function. J. Biol. Chem. 279:5621-5629
Norlén, L. Al-Amoudi, A. Dubochet, J (2003) A cryo-transmission electron microscopy study of skin barrier formation. J. Invest. Dermatol. 120:555-560
Norlén, L (2003) Skin barrier structure, function and formation – learning from cryo-electron microscopy of vitreous, fully hydrated native human epidermis. Int. J. Cosm. Sci. 25:1-18
Norlén, L (2003) Molecular skin barrier models and some central problems for the understanding of skin barrier structure and function. Skin Pharm. Appl. Physiol. 16(4):203-211
Norlén, L (2002) Does the single gel-phase exist in stratum corneum? J. Invest. Dermatol. 118(5):899-901
Norlén, L (2001) Skin barrier formation: the membrane folding model. J. Invest. Dermatol. 117(4):823-829
Norlén, L (2001) Skin barrier structure and function: the single gel-phase model. J. Invest. Dermatol. 117(4):830-836
Norlén, L. Engblom, J (2000) Structure-related aspects on water diffusivity in fatty acid-soap and skin lipid model systems. J. Control. Release 63(1-2):213-226
Norlén, L. Engblom, J. Anderson, M. Forslind, B (1999) A new computer-based evaporimeter system for rapid measuerments of water diffusion through stratum corneum in-vitro. J. Invest. Dermatol. 113(4):533-540
Norlén, L. Nicander, I. Lundh-Rozell, B. Ollmar, S. Forslind, B. (1999) Inter and intra individual differences in human stratum corneum lipid content related to physical parameters of skin barrier function. J. Invest. Dermatol. 112(1):72-77
Norlén, L. Nicander, I. Lundsjö, A. Cronholm, T. Forslind, B. (1998) A new HPLC-based method for the quantitative analysis of inner stratum corneum lipids with special reference to the free fatty acid fraction. Arch. Derm. Res. 290:508-516
Nicander, I. Norlén, L. Brockstedt, U. Lundh-Rozell, B. Forslind, B. Ollmar, S. (1998) Electrical impedance and other physical parameters as related to lipid content of human stratum corneum. Skin research and technology 4:213-221
Forslind, B. Norlén, L. Engblom J (1998) A structural model for the human skin barrier. In Colloid Science of Lipids. New Paradigms for self-assembly in Science and Technology. Progr. Colloid and Polym. Sci. 108:40-46
Nicander, I. Norlén, L. Forslind, B. Ollmar S (1998) Lipid content and electrical impedance. Curr Probl Dermatol. 26:165-76
Norlén, L. Emilson, A. Forslind, B. (1997) Stratum corneum swelling. Biophysical and computer assisted quantitative assessments. Arch. Derm. Res. 289(9): 506-513
Forslind, B. Engström, S. Engblom, J. Norlén, L. (1997) A novel approach to the understanding of human skin function. J. Dermatological Science (Japan) 14:115-125